This one is for all the marbles. Democrats seem poised to squeak through President Obama's landmark healthcare legislation late on Sunday, and the repercussions could be profound, especially on America's Middle East policy.
Forget for a moment that Obama's domestic approval ratings are at their lowest - less than 50 per cent - or that he has disappointed many around the world by failing to fulfil major objectives, like the closing of the Guantanamo Bay prison.
By scoring a victory of this scale - one that has eluded American presidents for close to 100 years - Obama could not only bring the bounce back to the step of his administration, but provide himself the bandwidth to focus on some of the changes he campaigned on.